Proceedings of the International scientific and practical conference ―Science in the Era of Globalization‖ (May 22-24, 2026) / Publisher website: www.naukainfo.com. - Zurich, Switzerland, 2026. - 353 p.

253 Chronic pelvic pain is chronic or persistent pain perceived in structures related to the pelvis of either males or females. Perceived indicates that the patient and clinician, to the best of their ability from the history, examination and investigations, have localised the pain as being discerned in a specified anatomical pelvic area.) It is often associated with negative cognitive, behavioural, sexual and emotional consequences, as well as with symptoms suggestive of lower urinary tract (LUT), sexual, bowel, pelvic floor or gynaecological dysfunction [2]. In the case of documented nociceptive pain that becomes chronic/persistent through time, pain must have been continuous or recurrent for at least three months (in accordance with ICD-11). For cyclical pain, a longer period of more than six months may be appropriate. Cyclical pain is included in the classification, particularly if there is evidence of central sensitisation, and dysmenorrhoea (hormonally dependent) needs to be considered as a chronic pain syndrome if it is persistent and associated with negative cognitive, behavioural, sexual or emotional consequences. Chronic pelvic pain may be subdivided into conditions with well-defined classical pathology (such as infection or cancer) and those with no obvious pathology but still including biological mechanisms. For the EAU‘s classification, the term ―specific disease-associated pelvic pain‖ has been accepted for the former, and ―chronic pelvic pain syndrome‖ for the latter. In the ICD-11, the former is called chronic secondary pelvic pain, and the latter chronic primary pelvic pain. Chronic primary pelvic pain syndrome (CPPPS) is the occurrence of chronic pain when there is no proven infection or other obvious local pathology that may account for the pain. It is often associated with negative cognitive, behavioural, sexual or emotional consequences, as well as with symptoms suggestive of LUT, sexual, bowel or gynaecological dysfunction. Chronic primary pelvic pain syndrome is a subdivision of chronic pelvic pain. Pain perception in CPPPS may be focused within a single organ, more than one pelvic organ, and even associated with systemic symptoms such as chronic fatigue syndrome (CFS), FM or Sjögren‘s syndrome. When the pain is localised to a single